I currently a few LCD monitors running from 1 PC, and thought I'd share the benefits with you.
However there are few requirements:
Windows XP Home or Professional or newer (best running SP2 (service pack2))
More than 1 video card or multiple head Video card(s)
Multiple Monitors & assoc cables
Decent Spec PC to Support configuration (Pentium 4, PCI(E) motherboard plenty of memory & above)
Rather than writing a detailed post, hence reinventing the wheel, I found a few good links that have plenty of information and could answer questions from there, wherever I can.